G-to-A – Hypermutation Filter Generation using Expectation Maximization

G-to-A

:: DESCRIPTION

G-to-A hypermutation filter generation using expectation maximization. Given a table of aggregated values and a set of preliminary filter constants, this program will construct a set of frequency distributions characterizing the hypermutated and non-hypermutated sequence subsets.

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::DEVELOPER

Stanford HIVDB Team

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux / Windows / MacOsX
  • Perl

:: DOWNLOAD

 G-to-A

:: MORE INFORMATION

Citation

A classification model for G-to-A hypermutation in hepatitis B virus ultra-deep pyrosequencing reads.
Reuman EC, Margeridon-Thermet S, Caudill HB, Liu T, Borroto-Esoda K, Svarovskaia ES, Holmes SP, Shafer RW.
Bioinformatics. 2010 Dec 1;26(23):2929-32. doi: 10.1093/bioinformatics/btq570.