ESTScan 3.03
:: DESCRIPTION
ESTScan is a program that can detect coding regions in DNA/RNA sequences, even if they are of low quality (e.g. EST sequences). ESTScan will also detect and correct sequencing errors that lead to frameshifts. ESTScan is not a gene prediction program , nor is it an open reading frame detector. In fact, its strength lies in the fact that it does not require an open reading frame to detect a coding region. As a result, the program may miss a few translated amino acids at either the N or the C terminus, but will detect coding regions with high selectivity and sensitivity.
::DEVELOPER
The SIB Swiss Institute of Bioinformatics
:: SCREENSHOTS
N/A
:: REQUIREMENTS
- Linux / Mac OS X
:: DOWNLOAD
:: MORE INFORMATION
Citation
Lottaz C, Iseli C, Jongeneel CV, Bucher P. (2003)
Modeling sequencing errors by combining Hidden Markov models
Bioinformatics 19, ii103-ii112.
Iseli C, Jongeneel CV, Bucher P. (1999)
ESTScan: a program for detecting, evaluating, and reconstructing potential coding regions in EST sequences.
Proc Int Conf Intell Syst Mol Biol.138-48.