Episomizer

:: DESCRIPTION

Episomizer is currently a semi-automatic computational pipeline to construct circular DNA structures through identifying SVs connecting the boundaries of highly amplified CNA segments followed by a graph theoretical algorithm that searches for cyclic graphs.

::DEVELOPER

Zhang (Jinghui Zhang) Lab,St. Jude Children’s Research Hospital

:: SCREENSHOTS

N/A

:: REQUIREMENTS

• Linux
• Perl
• R
• Python

:: DOWNLOAD

Episomizer

:: MORE INFORMATION

Citation

Xu K, Ding L, Chang TC, Chiang J, Mulder H, Wang S, Shaw TI, Wen J, Hover L, McLeod C, Wang YD, Easton J, Rusch M, Dalton J, Downing JR, Ellison DW, Zhang J, Baker SJ, Wu G.
Structure and evolution of double minutes in diagnosis and relapse brain tumors.
Acta Neuropathol. 2019 Jan;137(1):123-137. doi: 10.1007/s00401-018-1912-1.