CRISPR-SKIP 1.0.1

:: DESCRIPTION

The CRISPR-SKIP webtool identifies which exons can be skipped by editing the flanking G nucleotide of the conserved dinucleotide sequence at the splice acceptor site. The base editors supported in this webtool are BE3, SaKKH-BE3, VRER-BE3, VQR-BE3. The genome assembly and gene annotation used are GRCh38 and GENCODE release 26, respectively. Only primary PAMs are considered.

::DEVELOPER

Jun S. Song’s Research Group

:: SCREENSHOTS

N/A

:: REQUIREMENTS

• Web browser

:: DOWNLOAD

NO

:: MORE INFORMATION

Citation

Gapinske M, Luu A, Winter J, Woods WS, Kostan KA, Shiva N, Song JS, Perez-Pinera P.
CRISPR-SKIP: programmable gene splicing with single base editors.
Genome Biol. 2018 Aug 15;19(1):107. doi: 10.1186/s13059-018-1482-5. PMID: 30107853; PMCID: PMC6092781.