COMBASSOC allows the user to run any number of analyses with a choice of the programs RUNGC and/or SCANASSOC and/or RUNLR, all of which analyse data from cases and controls genotyped for multiple markers. COMBASSOC combines the p values that are obtained from these analyses into a single measure of significance and then carries out sequential Monte Carlo testing to test the overall significance. All of the analysis programs used by COMBASSOC, along with their full documentation, are provided in the support programs for GENECOUNTING.
:: MORE INFORMATION
Curtis, D., Vine, A. E. and Knight, J. 2008.
A simple method for assessing the strength of evidence for association at the level of the whole gene.
Advances and Applications in Bioinformatics and Chemistry 1:115-120.