ArtiFuse v1.0.0
:: DESCRIPTION
ArtiFusion is a tool to simulate artificial fusion events by modifying a given reference genome. The tool copies parts of the exonic sequence of gene A within the reference genome FASTA sequence into the downstream region of gene B and replaces the copied regions of gene A with Ns. The breakpoints are defined by using a size ratio between gene A and gene B and are always placed on exon-exon junctions. Intronic and intergenic regions remain unchanged.
::DEVELOPER
The Institute for Translational Oncology and Immunology(TrOn)
:: SCREENSHOTS
N/A
:: REQUIREMENTS
- Windows / Mac OsX / Linux
- Python
:: DOWNLOAD
:: MORE INFORMATION
Citation
Bioinformatics. 2019 Aug 2. pii: btz613. doi: 10.1093/bioinformatics/btz613.
ArtiFuse – Computational validation of fusion gene detection tools without relying on simulated reads.
Sorn P, Hohlsträter C, Löwer M, Sahin U, Weber D.