AlphaSeqOpt
:: DESCRIPTION
AlphaSeqOpt is a software package for determining the optimum distribution of sequencing resources within a population of interest. AlphaSeqOpt determines which individuals should be prioritised for sequencing and the total investment to be made in sequencing this individual. The aim of the algorithm is to capture, sequence and phase as many of the population haplotypes as possible for maximum sequence imputation ability into the rest of the population.
::DEVELOPER
:: SCREENSHOTS
N/A
:: REQUIREMENTS
- Linux/MacOsX / Windows
:: DOWNLOAD
:: MORE INFORMATION
Citation
Ros-Freixedes R, Gonen S, Gorjanc G, Hickey JM.
A method for allocating low-coverage sequencing resources by targeting haplotypes rather than individuals.
Genet Sel Evol. 2017 Oct 25;49(1):78. doi: 10.1186/s12711-017-0353-y. PMID: 29070022; PMCID: PMC5655873.