SH2PepInt 1.0.0 / SH3PepInt 1.0.0 – SH2-peptide / SH3-peptide Interaction Prediction

SH2PepInt 1.0.0 / SH3PepInt 1.0.0

:: DESCRIPTION

SH2PepInt has been developed to predict binding partners of 51 human SH2 domains. Peptides are restrained to 7 amino acids length, i.e. -2 to +4 amino acids around the pTyr position.

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SH3PepInt is an alignment-free, fast and sophisticated graph kernel based tool to predict SH3-peptide interactions. Total 69 built-in models are available for SH3-peptide predictions.

::DEVELOPER

Chair for Bioinformatics Freiburg

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Web browser

:: DOWNLOAD

 NO

:: MORE INFORMATION

Citation

PLoS One. 2013 May 17;8(5):e62732. doi: 10.1371/journal.pone.0062732. Print 2013.
Semi-supervised prediction of SH2-peptide interactions from imbalanced high-throughput data.
Kundu K1, Costa F, Huber M, Reth M, Backofen R.

Bioinformatics. 2013 Jul 1;29(13):i335-43. doi: 10.1093/bioinformatics/btt220.
A graph kernel approach for alignment-free domain-peptide interaction prediction with an application to human SH3 domains.
Kundu K1, Costa F, Backofen R.